Development and Validation of a High Performance Liquid Chromatographic Method for Determination of Etoposide in Biodegradable Polymeric Implants
نویسندگان
چکیده
Ana Gabriela Reis Solano* Faculdade de Farmácia, Universidade Federal de São João Del Rei, Rua Sebastião Gonçalves Coelho, 400, 35501-296 Divinópolis – MG / Departamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, 31270-901 Belo Horizonte – MG, Brasil Gisele Rodrigues da Silva Faculdade de Farmácia, Universidade Federal de São João Del Rei, Rua Sebastião Gonçalves Coelho, 400, 35501-296 Divinópolis – MG, Brasil Silvia Ligório Fialho Divisão de Desenvolvimento Farmacotécnico, Fundação Ezequiel Dias, Rua Conde Pereira Carneiro, 80, 30510-010 Belo Horizonte – MG, Brasil Armando da Silva Cunha Júnior e Gérson Antônio Pianetti Departamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627, 31270-901 Belo Horizonte – MG, Brasil
منابع مشابه
Development and Validation of a HPLC Method for Determination of Pefloxacin in Tablet and Human Plasma
Objective(s) Developing and validating a simple, efficient, reproducible and economic reversed phase high performance liquid chromatographic (RP-HPLC) method for the quantitative determination of pefloxacin in bulk material, tablets and in human plasma. Materials and Methods A shim-pack CLC-ODS column and a mobile phase constituting acetonitrile: 0.025 M phosphoric acid solution (13:87 v/v, ...
متن کاملSimple High-Performance Liquid Chromatographic Method for Determination of Ciprofloxacin in Human Plasma
A rapid, simple and sensitive high-performance liquid chromatography method was developed for determination of ciprofloxacin in plasma by means of ultraviolet detection. Ofloxacin was used as an internal standard and separation carried on a Novapak C18 column using a mobile phase of 0.01 M phosphate buffer (pH =2.6): methanol (82: 18 v/v). Extraction of drug was performed from plasma by liquid-...
متن کاملSimple High-Performance Liquid Chromatographic Method for Determination of Ciprofloxacin in Human Plasma
A rapid, simple and sensitive high-performance liquid chromatography method was developed for determination of ciprofloxacin in plasma by means of ultraviolet detection. Ofloxacin was used as an internal standard and separation carried on a Novapak C18 column using a mobile phase of 0.01 M phosphate buffer (pH =2.6): methanol (82: 18 v/v). Extraction of drug was performed from plasma by liquid-...
متن کاملRapid High Performance Liquid Chromatographic Determination of Risperidone in Human Plasma
A simple, rapid and sensitive high-performance liquid chromatographic (HPLC) method for the determination of risperidone in human plasma was developed. An HPLC system based on a Nucleosil C8 column (150?4 mm) and a UV detector (?= 280 nm) were used. A mixture of sodium dihydrogen phosphate buffer-acetonitrile (55:45, v/v) adjusted to pH 6.0 at a flow rate of 1.5 ml min-1 was used as mobile phas...
متن کاملComparison of Microbiological and High-Performance Liquid Chromatographic Methods for Determination of Clarithromycin Levels in Plasma
An agar well diffusion bioassay method for determination of clarithromycin in human plasma, using Micrococcus Luteus ATCC 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (HPLC) method with UV detection. Spiked plasma was used to prepare standard and control samples for both methods. The results of the bioassay analyses with spiked plasma samples...
متن کامل